- Summer Circuit Trophy – Complete Summer Circuit in My Player.
- Training Camp Trophy – Complete Training Camp in My Player.
- Play in the NBA Trophy – Play in an NBA game in My Player.
- 30 Assists Trophy – Record 30 assists or more with any team.
- 10 Blocks Trophy – Record 10 blocks or more with any team.
- 15 Steals Trophy – Record 15 steals or more with any team.
- Rebound + 10 Trophy – Win the rebound battle by a margin of + 10 with any team.
- 15 Threes Trophy – Make 15 three pointers or more with any team.
- Defensive FG% Trophy – Hold the opposing team’s FG% below 40% with any team.
- Lights Out Trophy – FG% over 60% for the game [min 40 FGA’s] with any team.
- Track Meet Trophy – Score at least 20 fastbreak points with any team.
- Second Unit Trophy – Score at least 40 bench points with any team.
- Inside Domination Trophy – Score at least 70 points in the paint with any team.
- Good Hands Trophy – Record at least 20 assists with no more than 5 turnovers with any team.
- All-Hustle Trophy – Record at least 5 offensive rebounds, 5 blocks and 5 steals with any team.
- All-Hearted Trophy – Start the 4th period losing by 5 or more points and win the game with any team.
- 3-for-All Trophy – Make at least 10 3pt FG’s while shooting at least 45% from 3pt range with any team.
- Ice Water Trophy – FT% over 85% with at least 10 FTA’s with any team.
- Lockdown Trophy – Record at least 5 blocks and 5 steals with any team.
- Celtics vs Lakers Trophy – User controlled team from either side must win against opponent at All-Star difficulty or higher.
- East vs West Trophy – User controlled team from either side must win against opponent at All-Star difficulty or higher.
- Rookie Challenge Trophy – User controlled Rookie team must beat the Sophomores at All-Star difficulty or higher.
- 3pt Shootout Trophy – Win the 3pt Shootout.
- Create-a-Player Trophy – Create a Player.
- 2K Beats Playlist Trophy – Create a 2K Beats Playlist.
- Ranked Match Trophy – Win one online ranked match.
- 3 Ranked Streak Trophy – Win 3 ranked matches in a row.
- 5 Ranked Streak Trophy – Win 5 ranked matches in a row.
- 5 Ranked Matches Trophy – Win 5 ranked matches total.
- Crew Game Trophy – Win one online crew game.
- Pick-up Game Trophy – Win one online pick-up game.
- It’s Better to Give Trophy – Share any file type through 2K Share.
- G Performance Trophy – Record at least 25 pts, 3 stls and 2 blks with Dwayne Wade.
- LeBron James Trophy – Record at least 25 pts, 8 rebs, and 8 assts with LeBron James.
- Kobe Bryant Trophy – Record at least 50 pts with Kobe Bryant.
- Brandon Roy Trophy – Record at least 25 pts and 6 assts with Brandon Roy.
- Danny Granger Trophy – Record at least 30 pts, 3 threes and 2 blks with Danny Granger.
- Dwight Howard Trophy – Record at least 20 pts, 15 rebs and 3 blks with Dwight Howard.
- Kevin Durant Trophy – Record at least 35 pts and 6 rebs with Kevin Durant.
- Carmelo Anthony Trophy – Record at least 40 pts with Carmelo Anthony.
- Chris Paul Trophy – Record at least 20 pts, 10 assts and 3 stls with Chris Paul.
- Deron Williams Trophy – Record at least 20 pts and 12 assts with Deron Williams.
- Yao Ming Trophy – Record at least 20 pts, 10 rebs and 3 blks with Yao Ming.
- Dirk Nowitzki Trophy – Record at least 30 pts and 8 rebs with Dirk Nowitzki.
- Sprite Slam Dunk Trophy – Win the Dunk Contest using LeBron James.
- Dunk-Off Trophy – Defeat any challenger in a Dunk-Off.
- 10 Ranked Matches Trophy – Win 10 ranked matches total.
- 20 Ranked Matches Trophy – Win 20 ranked matches total.
- All-NBA Trophy – Earn every trophy in NBA 2K10.