- Vault 101 Citizenship Award – Got the Pip-Boy 3000
- The G.O.A.T. Whisperer – Took the G.O.A.T.
- Escape! – Completed “Escape!”
- Following in His Footsteps – Completed “Following in His Footsteps”
- Galaxy News Radio – Completed “Galaxy News Radio”
- Scientific Pursuits – Completed “Scientific Pursuits”
- Tranquility Lane – Completed “Tranquility Lane”
- The Waters of Life – Completed “The Waters of Life”
- Picking up the Trail – Completed “Picking up the Trail”
- Rescue from Paradise – Completed “Rescue from Paradise”
- Finding the Garden of Eden – Completed “Finding the Garden of Eden”
- The American Dream – Completed “The American Dream”
- Big Trouble in Big Town – Completed “Big Trouble to Big Town”
- The Superhuman Gambit – Completed “The Superhuman Gambit”
- The Wasteland Survival Guide – Completed “The Wasteland Survival Guide”
- Those! – Completed “Those!”
- The Nuka-Cola Challenge – Completed “The Nuka-Cola Challenge”
- Head of State – Completed “Head of State”
- The Replicated Man – Completed “The Replicated Man”
- Blood Ties – Completed “Blood Ties”
- Oasis – Completed “Oasis”
- The Power of the Atom – Completed “The Power of the Atom”
- Tenpenny Tower – Completed “Tenpenny Tower”
- Strictly Business – Completed “Strictly Business”
- You Gotta Shoot ‘Em in the Head – Completed “You Gotta Shoot ‘Em in the Head”
- Stealing Independence – Completed “Stealing Independence”
- Trouble on the Homefront – Completed “Trouble on the Homefront”
- Agatha’s Song – Completed “Agatha’s Song”
- Reilly’s Rangers – Completed “Reilly’s Rangers”
- Reaver – Reached Level 8 with Bad Karma
- Mercenary – Reached Level 8 with Neutral Karma
- Protector – Reached Level 8 with Good Karma
- Harbinger of War – Reached Level 14 with Bad Karma
- Pinnacle of Survival – Reached Level 14 with Neutral Karma
- Ambassador of Peace – Reached Level 14 with Good Karma
- Doesn’t Play Well with Others – Killed 300 people
- Slayer of Beasts – Killed 300 creatures
- Psychotic Prankster – Placed a grenade or mine while pickpocketing
- Devil – Reached Level 30 with Bad Karma
- True Mortal – Reached Level 30 with Neutral Karma
- Messiah – Reached Level 30 with Good Karma
- Take it Back! – Completed “Take it Back!”
- Scourge of Humanity – Reached Level 20 with Bad Karma
- Paradigm of Humanity – Reached Level 20 with Neutral Karma
- Last, Best Hope of Humanity – Reached Level 20 with Good Karma
- Weaponsmith – Made one of every custom weapon
- Silver-Tongued Devil – Won 50 Speech Challenges
- Data Miner – Hacked 50 terminals
- Keys are for Cowards – Picked 50 locks
- One-Man Scouting Party – Discovered 100 locations
- Yes, I Play with Dolls – Collected 10 Vault-Tec Bobbleheads
- Aiding the Outcasts – Completed “Aiding the Outcasts”
- The Guns of Anchorage – Completed “The Guns of Anchorage”
- Paving the Way – Completed “Paving the Way”
- Into the Pitt – Completed “Into the Pitt”
- Unsafe Working Conditions – Completed “Unsafe Working Conditions”
- Mill Worker – Found 100 Steel Ingots
- Death From Above – Completed “Death From Above”
- Shock Value – Completed “Shock Value”
- The Local Flavor – Completed “The Local Flavor”
- Walking with Spirits – Completed “Walking with Spirits”
- Bog Walker – Discovered all locations within Point Lookout
- Not of This World – Completed “Not of This World”
- Among the Stars – Completed “Among the Stars”
- Alien Archivist – Collected all Alien Captive Recordings
- The Bigger They Are… – Kill all the Super Mutant Behemoths
- Vault-Tec C.E.O. – Collected 20 Vault-Tec Bobbleheads
- Operation: Anchorage – Completed “Operation: Anchorage”
- Free Labor – Completed “Free Labor”
- Who Dares Wins – Completed “Who Dares Wins”
- A Meeting of the Minds – Completed “A Meeting of the Minds”
- This Galaxy Ain’t Big Enough… – Completed “This Galaxy Ain’t Big Enough…”
- Platinum Trophy – Collect all other 50 Trophies for this Trophy