- Completed Chapter 1 – 1 – Complete Chapter 1 – 1 on any difficulty setting.
- Completed Chapter 1 – 2 – Complete Chapter 1 – 2 on any difficulty setting.
- Completed Chapter 2 – 1 – Complete Chapter 2 – 1 on any difficulty setting.
- Completed Chapter 2 – 2 – Complete Chapter 2 – 2 on any difficulty setting.
- Completed Chapter 2 – 3 – Complete Chapter 2 – 3 on any difficulty setting.
- Completed Chapter 3 – 1 – Complete Chapter 3 – 1 on any difficulty setting.
- Completed Chapter 3 – 2 – Complete Chapter 3 – 2 on any difficulty setting.
- Completed Chapter 3 – 3 – Complete Chapter 3 – 3 on any difficulty setting.
- Completed Chapter 4 – 1 – Complete Chapter 4 – 1 on any difficulty setting.
- Completed Chapter 4 – 2 – Complete Chapter 4 – 2 on any difficulty setting.
- Completed Chapter 5 – 1 – Complete Chapter 5 – 1 on any difficulty setting.
- Completed Chapter 5 – 2 – Complete Chapter 5 – 2 on any difficulty setting.
- Completed Chapter 5 – 3 – Complete Chapter 5 – 3 on any difficulty setting.
- Completed Chapter 6 – 1 – Complete Chapter 6 – 1 on any difficulty setting.
- Completed Chapter 6 – 2 – Complete Chapter 6 – 2 on any difficulty setting.
- Completed Chapter 6 – 3 – Complete Chapter 6 – 3 on any difficulty setting.
- Recruit – Complete all chapters on Amateur.
- Soldier – Complete all chapters on Normal.
- Egg Hunt – Find all 4 types of eggs.
- A Friend in Need – Save partner 10 times when HELP is displayed.
- Lifeguard – Save partner 10 times when DYING is displayed.
- Exploding Heads – Pull off 20 headshots.
- A Cut Above – Defeat 5 enemies with the Knife.
- Cattle Prod – Defeat 30 enemies with the Stun rod.
- Crowd Control – Defeat 30 enemies with the Gatling gun.
- Bull’s-eye – Defeat 30 enemies with the Longbow.
- Get Physical – Defeat 20 enemies with physical attacks.
- The Works – Chain the maximum number of combos together in one go.
- Fireworks – Shoot an enemy Molotov cocktail, dynamite stick, or hand grenade.
- Meat Shower – Defeat 3 Majini with one grenade or proximity bomb.
- Go into the Light – Defeat 2 enemies with one flash grenade.
- Ride the Lightning – Defeat a Majini using the electric current from a transformer.
- Stop, Drop, & Roll – Defeat 3 Majini at once by setting oil canisters on fire.
- Baptism by Fire – Defeat 3 Majini at once with a drum or gas tank explosion.
- Masters of Removing – Work together to save someone special.
- SECRET Bad Blood – During the first fight with Wesker, damage him a set number of times.
- Egg on Your Face – Defeat a Majini with a rotten egg.
- Heart Stopper – Defeat a certain enemy by stabbing it in the heart.
- Army of One – Win 30 matches in Slayers.
- Eye of the Tiger – Win 30 matches in Survivors.
- Keep the Good Times Rolling – Chain a 20-defeated combo in Slayers.
- It Takes Two to Tango – Chain a 40-defeated combo in Team Slayers.
- It’s All About the Points – Score at least 40,000 points in Survivors.
- There’s no “I” in Team – Score at least 80,000 points in Team Survivors.
- Let’s Get This Party Started! – Unlock all selectable characters in Versus.
- Who Do You Trust? – Build up a certain level of trust with your partner.
- Drive By – Stop an armored truck by taking out the driver.
- Be the Knife – Deflect a bow gun arrow with your knife.
- Lead Aspirin – Defeat a Majini with a headshot while it’s jumping.
- All Dressed Up – Purchase all available alternative costumes in Bonus Features.
- Stockpile – Obtain all available weapons.
- Take It to the Max – Completely upgrade all weapons.
- They Belong in a Museum – Obtain all treasures in the game.
- Badge of Honor – Find all the BSAA emblems.
- They’re ACTION Figures! – Collect all the figurines.
- Veteran – Complete all chapters on Veteran.
- The Team That Slays Together… – Win 30 matches in Team Slayers.
- We Will Survive – Win 30 matches in Team Survivors.
- Bringing the Pain – Defeat 100 players using physical attacks in Versus.
- SECRET War Hero – Complete all chapters on Professional.
- SECRET Platinum Trophy – Congratulations! You’ve overcome all your fears in RESIDENT EVIL 5!