- Just Scratched the Surface – Collect all Dead Drops in the Neon District
- Further Down the Rabbit Hole – Collect all Dead Drops in the Warren
- You’re so Sly – Collect all Dead Drops in the Historic District
- Junior Geologist – Find 25% of the Shards
- Member of the Mieral Club – Find 50% of the shards
- Rockhound – Find 100% of the shards
- Frequent Flyer – Travel 5 kilometers using Static Thrusters
- Hotfoot – Travel 25 kilometers while riding the rails
- Electric Hobo – Ride the train for 2 kilometers
- Casey Jones – Take down 25 enemies while riding on a moving train
- Road Kill – Take down 25 enemies while riding on the roof of a moving vehicle
- Drop Everything – Thunder Drop for a total distance of at least 500 meters
- AC/DC – Drain 750 megawatts of power from Empire City
- Get Off My Cloud – Get 100 High Fall take downs
- Red Baron – Take down 100 enemies while they are airborne
- Fish in a Barrel – Kill 50 enemies by using water
- True Potential – Purchase every upgrade for a single power
- Oh, You’ve Done This Before – Take down 50 enemies by sticking them with a grenade
- The Hunger – Bio Leech 100 enemies
- Doctor Cole – Heal 250 pedestrians
- Good Eats – Good guys feed the needy
- Evil Eats – Bad guy never share their food
- Good Riot – Good guys stand up and take the heat
- Evil Riot – Bad guys love starting riots
- Good Train – Good guys proactively facilitate transportation solutions
- Evil Train – Bad guys make it clear who the boss is
- Good Exposure – Good guys are heroes to others
- Evil Exposure – Bad guys love to be seen
- Good Sphere – Good guys put a stop to the madness
- Evil Sphere – Bad guys always want more power
- Good Intentions – Good guys work for the greater good
- Evil Intentions – Bad guys can’t say goodbye
- Stunt Man – Complete any one stunt from the stunt list
- Stunt Coordinator – Complete 10 of the stunts on the stunt list
- Good Finish – Beat the game as a hero
- Evil Finish – Beat the game while Infamous
- Community Ogranizer – Take over all territory in the Neon District
- Civic Leader -Take over all territory in the Warren
- Urban Designer – Take Over all territory in the Historic District
- Evil to the Core – Purchase every negative Karma upgrade for each power
- True hero – Purchase every postive Karma upgrade for each power
- Good Two Shoes – Reach full positive Karma
- Truly Infamous – Reach full negative Karma
- Stunt Master – Complete all the stunts on the stunt list
- Hard Finish – Finish story mode on Hard, without changing the difficulty setting
- inFamous Platinum Trophy – Collect all other inFamous trophies
4 Secret Trophies